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Medically reviewed by Sanjai Sinha, MD. It effectively brings down blood pressure by reducing levels of certain body chemicals. Diminished blood flow through arteries of the heart. Catapres ® (clonidine hydrochloride, USP) is a centrally acting alpha-agonist hypotensive agent available as tablets for oral administration in three dosage strengths: 0. Rx only Prescribing Information. Consult your doctor if pregnant or breastfeeding Catapres tablets are taken by mouth, with or without food, usually twice, once in the morning and once at bedtime. A disorder of the blood vessels of. Raised red swellings on the skin, lips, tongue, or in the throat. 3 mg); oral tablet, extended release (0. Common side effects of Catapres-TTS include: dry mouth or throat, dizziness, drowsiness, tiredness, fatigue, nervousness, and ; constipation that often go away after several doses. This is not a complete list of side effects and others may occur. 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Use of Catapres TTS (patch) may result in a rash, and a switch to Catapres tablets may or may not cause this side effect. Brand names: Catapres, Kapvay Dosage forms: oral tablet (0. Heart pounding with any exertion. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. If you experience any of the following symptoms, call your doctor immediately or get emergency medical treatment: rash. Clonidine (Catapres) is a unique blood pressure drug that was first approved by the FDA in 1974. Before starting the medication, inform the doctor of any health problems that you are currently suffering from It is recommended to give Clonidine 90 minutes to 2 hours before the expected anxiety-inducing event. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 Catapres (clonidine) is a prescription medication used to treat high blood pressure (hypertension). 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